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Needle Biopsy of the Liver

What is a liver biopsy?

A percutaneous liver biopsy needle aspiration provides a sample of liver tissue that can be used to diagnose most disorders of the liver, such as rejection, inflammation, infection, steatosis, cirrhosis, confirm the presence of cancer, or assess the effects of hepatotoxic drugs. Repeat biopsies reveal the progress and response to treatment of chronic liver diseases such as active hepatitis.

Pre-biopsy Preparation
You should be NPO for 4-6 hours but please take all your medications. Inform your doctor before hand if you are on Aspirin, blood thinner like, Comadin' antibiotics, allergy, have a bleeding tendencies or blood disorder. You will be asked to empty your bladder and put on a hospital gown. Intravenous line will be inserted and your vitals respiratory rate, pulse rate and blood pressure will be monitored. The nurse or doctor will ask you some questions and position you on your back with your right arm extended above your head or left arm along your side on a flat bed. The doctor will locate the site of the biopsy on your right side (lower chest and upper abdomen) by percussion or ultrasound.

Taking the biopsy
The doctor will clean the area with cleaning solutions and cover it with clean drapes, please do not touch this sterile area. The doctor will instruct you on your breathing pattern, as you need during the biopsy to breath in then exhale all air then hold while the doctor is doing the procedure. After the doctor fInish the procedure, he will tell you to breath nonnally and Bx site will be covered by dressing.

Post Biopsy
You will be instructed to roll on your right side for 2 hours on the site of the biopsy in order to compress the area and prevent bleeding. You will stay in bed for a total of 6 hours. (Minimum of 2 hours on your right side and 4 hours on your back). Your pulse rate, respiratory rate, blood pressure will be monitored. Inform your nurse if you have i) severe pain, ii) dizziness. After biopsy for 2 hours, avoid:

  1. food

  2. cough

  3. staining

  4. avoid lifting and strenous activity for about a week.

Complications
Most patients recovered with no complication 99%, but serious complication (1 %) can happen.

  1. Bleeding into the abdomen or liver leading to severe pain.

  2. A pneumothorax due to air in pleural space in the chest leading to sudden chest pain and shortness of Gallbreath.

  3. Perforation of the bladder.

  4. Bleeding into bile duct which can lead to hematemesis, melena, abdominal pain, and jaundice.

  5. Bacteremia leading to fever.

Minor complications are more common like mild pain at site of biopsy or pain radiating to shoulder, which should be settled before you leave the procedure area

 

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